Studies of In-Vitro Amlodipine and Arsenic Displacement Interaction at Binding Sites of Bovine Serum Albumin

studies of in-vitro amlodipine and arsenic displacement interaction at binding sites of bovine serum albumin

in this study, the binding of amlodipine (a ca ++ channel blocker) and arsenic (metalloid) to bovine serum albumin (bsa) was studied by equilibrium dialysis(ed) method in order to have an insight into their binding chemistry to bsa. free amlodipine concentration was increased due to addition of arsenic which reduced the binding of the compounds to bsa. however, the free fraction was not increas...

interaction of 6-mercaptopurine with bovine serum albumin and displacement from the binding sites by quercetin and rutin

Interaction of Phthalocyanine with Egg albumin and Bovine serum albumin

The interaction of bovine serum albumin ( BSA) and egg albumin with water solublephthalocyanine, cobalt (ΙΙ) 4, 4′ , 4′′, 4′′′- tetrasulfophthalocyanine ( CoTSPc) , has been studiedby the UV- Vis method at pH 7.0 and five different temperatures 20, 25, 30, 35 and 40°C. Theformation constants have been elucidated by using spectrophotometric titration and computerSQUAD program data refinement. Th...

Spectroscopic, Thermodynamic and Molecular Docking Studies on Interaction of Toxic Azo Dye with Bovine Serum Albumin

Investigation on interaction of azo dyes with bovine serum albumin as carrier protein will be important in the field of toxicology because of distribution and transportation of dyes in blood. In this regard, the interaction between the azo dye, trisodium (4E)-3-oxo-4-[(4- sulfonato-1- naphthyl) hydrazono] naphthalene-2,7-disulfonate (C20H11N2Na3O10S3), known as Amaranth and bovine serum albumin...

Comparative Binding Affinities of Flavonoid Phytochemicals with Bovine Serum Albumin

Dietary flavonoids show beneficial effects in the prevention of chronic diseases. However, flavonoid bioavailability is poor, probably due to their interaction with serum albumins. In the current work, the binding interactions of eight related flavonoids, sharing a similar core structure, with bovine serum albumin (BSA) were investigated by fluorescence spectroscopy. The binding affinities of t...

Comparative Binding Affinities of Flavonoid Phytochemicals with Bovine Serum Albumin

Dietary flavonoids show beneficial effects in the prevention of chronic diseases. However, flavonoid bioavailability is poor, probably due to their interaction with serum albumins. In the current work, the binding interactions of eight related flavonoids, sharing a similar core structure, with bovine serum albumin (BSA) were investigated by fluorescence spectroscopy. The binding affinities of t...